Objective to optimize the disintegrating agent from tripterygium glucosides dispersible tablet and study its quality 摘要目的优选雷公藤多苷分散片的崩解剂,并考察其成品的质量。
Conclusion l - hpc and mcc can be prepared with disintegrating agent from tripterygium glucosides dispersible tablet 结论混合的低取代羟丙纤维素和微晶纤维素可作为雷公藤多苷分散片的崩解剂。
Method the dispersible tablet was prepared with different matching adjuvants as disintegrating agent , and the quality was detected 方法采用不同配比的辅料为崩解剂,制备分散片,并进行成品质量考察。
Result the preparation showed good quality when 11 : 3 matching hyprolose ( l - hpc ) and microcrystalline cellulose ( mcc ) disintegrating agent 结果11 : 3配比的低取代羟丙纤维素和微晶纤维素作为雷公藤多苷分散片的崩解剂,制剂的性能良好。
Yh - e is mainly used in medicine , toothpaste , and food service industry , and it was widely used as the sorbent and ointment of medicine , cementing agent , disintegration agent , the stabilizer of the laminated medicine , and the toothpaste additives 2 yh - e主要用于医药,牙膏,食品等行业。广泛用作药物的吸附剂和药膏,片状药无的粘合剂,崩解剂和稳定机,牙膏添加剂等。
Brown yellow or red brown molding powder , has weak special smell , can dissolve in water and ethanol , not dissolve in ethyl ether and chloroform , good stability , no stimulate , has strong extermination effect to bacteria , virus , epiphyte , mildew and sporule . application 由于pvpp的高分子量和交联结构,不溶于水但遇水能迅速将水引入,促使其网络结构膨胀产生崩解作用,所以pvpp是医药上广泛应用于片剂颗粒剂及胶囊剂的崩解剂填充剂。
Through systematical review of previous literatures , combining with research status of dispersible tablets , the functions of disintegrating agents , adhesives , other excipents of dispersible tablets and the influences of preparation methods on disintegration and dissolubility of dispersible tablets were summarized 本文通过系统查阅以往国内外文献资料,结合国内分散片研究现状,对分散片处方中的崩解剂、粘合剂及其它辅料的作用和制备方法对分散片崩解性能和溶出性能的影响进行综述