The protein encoded by the ptch gene normally inhibits another protein , smoothened 。在痣样基底细胞瘤综合病徵中,当
Objective to investigate the best surgical methods on the therapy of basaloma 摘要目的探讨基底细胞瘤的最佳手术治疗方式。
Bcc is a common skin tumor in humans with over a million cases a year worldwide , showing a continuing increase in incidence 基底细胞瘤是一种常见的皮肤癌,全世界每年有超过一百万宗新症,而且发病率不断地上升。
Conclusion cosmetic surgery is the first choice to treat basaloma , and proper surgical methods can get good healing and beautiful appearance 结论基底细胞瘤首选是手术治疗,适宜的手术方式可取得治愈且美观的效果。
Recently , insight into the molecular origins of bccs came from the identification of mutations in the patched gene ( ptch ) in patients with nevoid basal cell carcinoma syndrome ( ptch )的突变,对基底细胞瘤的发生开始有了更深了解。正常情况下,
Treatment of bcc is usually by surgical removal , but recurrence is common because the full tumor is difficult to remove , and repeated surgeries are often necessary 基底细胞瘤通常是靠外科切除来治疗,但由于很难完全清除肿瘤,复发情况仍很常见,所以常常需要再次的外科切除。
Accordingly 6 types were categorized : i . e . basal cell focal hyperplasia , basal cell atypical focal hyperplasia , basal cell adenomatoid hyperplasia , basal cell atypical adenomatoid hyperplasia , adenoid basal cell tumor and basal carcinoma 本组特征表现为6型,即基底细胞灶性增生、基底细胞非典型性灶性增生、基底细胞腺瘤样增生、基底细胞非典型性腺瘤样增生、腺样基底细胞瘤和基底细胞癌。
The research by dr lam and his collaborators from university of california , san francisco and genetech , inc . which was published in nature , a world s leading scientific journal , identifies an activating mutation in the smoothened ( smo ) gene in sporadic bccs 的科学家合作研究,发现从散发性基底细胞瘤病例中鉴定出圆滑蛋白基因的一种活化突变,使圆滑蛋白基因变成肿瘤基因,导致基底细胞瘤的出现。
Bccs usually arise in elderly light - skinned people as sporadic tumors , but are also a major feature of the nevoid basal cell carcinoma syndrome , an unusual genetic disorder characterized primarily by cancer susceptibility and some embryonic abnormalities 这种癌症在浅肤色的年长者中,常以散发性肿瘤表现出来,它也是痣样基底细胞瘤综合病徵的主要徵状,痣样基底细胞瘤是一种特别的遗传疾病,主要以癌症易感性及胚胎异常为特徵。