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binding site中文是什么意思

  • 接合点
  • 结合部位,结合位点
  • 束缚位置

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  • 例句与用法
  • The cdna of subunit b was 1470 nucleotides long coding for 489 amino acids with a conservative atp binding site " 324 - sgsit - 328 " and a predicted molecular mass of 54 . 29 kda . amino acid sequence alignment analysis suggested that the v - h + - atpase b subunit of s . salsa had high homology with other reported v - h + - atpase subunit b . the h + - atpase subunit h from s . salsa was a hydrophilic protein with 465 amino acids and a predicted molecular mass of 52 . 8 kda , which was encoded by a cdna with 1398 nucleotides in orf . blast analysis indicated that the h + - atpase subunit h from s . salsa had a high amino acid sequence identity with those coming from plants , but had relatively low sequence identity with those coming from other species
    盐地碱蓬液泡膜h ~ + - atpaseb亚基是由1470个核苷酸编码的长达489个氨基酸的多肽,分子量约54 . 29kda ,存在保守的atp结合序列“ 324 - sgsit - 328 ” ,与其他物种来源的v - h ~ + - atpaseb亚基具有较高的氨基酸序列相似性; h亚基为亲水多肽,开放阅读框长达1398 - bp ,编码465个氨基酸残基,分子量约52 . 8kda ,与植物来源的液泡膜h ~ + - atpaseh亚基具有较高的氨基酸序列相似性,而与其他物种来源的v - h ~ + - atpaseh亚基同源性较低; c亚基开放阅读框为495 - bp ,编码164个氨基酸残基,分子量约16 . 6kda ,为一跨膜多肽,存在四个可能的跨膜区。
  • Part ii this paper has minutely studied the interaction between au ( iii ) and serum albumin . the binding of au ( iii ) to human serum albumin ( hsa ) or bovine serum albumin ( bsa ) has been studied by equilibrium dialysis at ph ( 7 . 43 + 0 . 02 ) . the scatchard analysis indicates that there exists several strong binding sites of au ( iii ) in both hsa and bsa . a notable hysteretic effect has been observed in the interaction of au ( iii ) with hsa or bsa using uv - visible spectrometry at ph ( 7 . 43 + 0 . 02 ) , which shows that the binding between au ( iii ) with hsa or bsa may induce a slow transition of hsa or bsa from the conformation of weaker affinity for au ( iii ) to one of stronger affinity ( a - b transition ) . the rate constants and activation parameters of this transition parameters of this tansition were measured and discussed . the binding equilibrium has project supported by the national science foundation of china ( no . 299621001 ) , and the foundation for talents of the ten hunred thousand in guangxi
    第二部分:生理ph ( 7 . 43 0 . 02 )条件下,用平衡透析法和紫外光谱,荧光光谱研究了金( )与人血清白蛋白( humanserumalbumin ,简称hsa )或牛血清白蛋白( bovineserumalbumin ,简称bsa )的结合。 scatchard图分析表明,金( )在hsa或bsa中有强弱两类结合部位,通过计算机拟合获得结合的逐级稳定常数值。利用荧光猝灭法计算出金( ) - hsa和金( ) - bsa体系的stem - volmer常数和双分子猝灭速率常数。
  • Subsequently , the binding of ( 35 ) ~ s - cam and a . thaliana protoplasts were processed , including association , dissociation , competitive and saturation analysis . the results show the binding of ( 35 ) ~ s - cam and protoplasts is rapid , reversible , saturable and sensitive to proteinase ; otherwise the specificity of binding was assessed with different competitors . k _ ( d ) of 9 . 2 nm and about 25 , 000 binding sites per protoplast were gained through saturation analysis
    随后,对~ ( 35 ) s - cam和拟南芥原生质体的结合进行了受体学分析,包括结合、解离、竞争性和饱和分析,结果显示~ ( 35 ) s - cam和拟南芥原生质体的结合具有结合快速性、可逆性、竞争特异性和浓度饱和性,从饱和分析可以得出k _ d约为9 . 2nm ,每个原生质体表面大约含有25 , 000个结合位点,并且其结合对蛋白酶敏感。
  • Our previous work has also shown that there is a cam - binding site within maize cytoplasmic hsp70 and that hsp70 binds cam in a ca2 + - dependent manner ( sun et al , 2000 ) . the high conservation of cam - binding suquence implies that the binding of cam to hsp70 might have an important biological function
    先前我们在玉米中,通过体外结合和竞争抑制实验证明了热激蛋白家族中最重要的成员之一纯化的细胞质hsp70能与cam结合,并且证明了玉米细胞质hsp70中存在一个非常保守的21个氨基酸组成的cam结合序列。
  • This article mainly discusses the challenges , research approaches and recent developed tools in the field of protein function prediction and the ways by which these issues change the process of drug discovery , including homology - based annotation transfer , sequence motifs and patterns , information on 3d structure , sub - cellular localization , posttranslational modifications , binding sites and functional residues , protein - protein interactions
    摘要简述了在蛋白质功能预测领域中的研究方法和最新研发工具所面临的挑战,并讨论蛋白质功能预测是如何改变药物开发进展的,具体包括:基于序列同源性分析的注释转移、序列基元和模式增加了注释转移的说服力、 3d结构信息可以精炼注释转移、亚细胞定位、翻译后修饰、结合位点和功能残基、蛋白质之间的相互作用。
  • The change of agglutinating activity , cd spectrum and fls of lra in different temperature , ph and different chemicals indicated that lra had partial hemagglutinating activity at ph2 . 0 ( 50 % ) , a temperature above 100 ( 60 % ) and after modified by n - bromosuccinimide ( mbs ) , the activity lost completely , modified by depc , the lra had a little activity , the other groups modified such as arg , tyr , glu , asp did n ' t effect the hemagglutinating activity of lra . the result indicated that trp residues were essential to the hemagglutinating activity and were involved in carbohydrate - binding site
    研究不同温度、 ph和基团特异性化学修饰后lra凝血活性和促淋巴细胞有丝分裂的变化、圆二色谱和荧光光谱的变化,当温度达80以上时,活性开始下降,到100时活性有60 %保留:当ph为2时,活性保留50 % , ph为4一12对活性的影响不大;用nbs修饰trp后, t即的旦一叫睬基的破坏使活性完全丧失,表明trp对凝血活性是至关重要的, arg 、 tyr 、 glu 、 asp被修饰后, lra的凝血活性并未受到大的影响,但tyr修饰后lra的促有丝分裂活性降低
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  • 百科解释
In biochemistry, a binding site is a region on a protein, DNA, or RNA to which specific other molecules and ions?in this context collectively called ligands?form a chemical bond.
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Last modified time:Sun, 10 Aug 2025 00:29:56 GMT

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