With the arrival of the post - genome era and recent development of new , high - throughput technologies to mine data in biology , vast amounts of sequence data are flooding the dna and protein databases so rapidly that there is a strong need for efficient as well as effective computational tools to handle these data 随着后基因组时代的到来以及一些新的高通量信息提取技术的开发, dna和蛋白质序列数据库中的信息量以爆炸式增长。生命科学研究已经进入了深深依赖计算机和网络的时代。在所有的计算机工具中,多序列对齐占据核心地位。