We have made comparisons among current methods for gene mapping . most methods based on linkage analysis and association analysis considers one marker at a time and does not take into account the correlated structure of multiple linked markers 我们对比了现有的基因定位分析方法,基于连锁分析和关联分析的基因定位方法多是针对单个疾病特征标记来研究,忽略了多个可能疾病特征标记间复杂互作的综合效应。