The metal ions and its coordination environment are generally the active center of the biological molecules , so the study on the metal ions and their micro - environment is of great significance 金属离子及其配位环境往往就是生物分子的活性中心,因而对金属离子及其微环境的研究具有重要意义。
The cd spectrum showed that the denaturation was a two - steps " progress . first , lra did n ' t lose activity despite of its structure change because the change was out of the active center 用depc对组氨酸的p一咪哇基进行特异化学修饰后,其凝血活性有明显的下降,表明p一咪哇基是凝血活性的必需基团。
The interlayer distance of heptylamine intercalation complex is smaller than butylamine intercalation complex . polyamine molecules formed a bent conformation in the interlayer space of a - zpmpp and formed several intercalation phases for its muti - active center 多胺分子在(脯氨酸一n一甲基磷酸一磷酸氢)结的层板间呈弯曲排列,多胺分子由于有多个活性中心可以形成多个插层相。
Second , the active center was destroyed and lra began to lose its agglutinate activity . so lra has a comparatively stable structure . the fls of lra with different temperature and ph also showed there was little change 而圆二色谱的研究表明结构的变化先于活性的变化,先是结构开始变化,但活性中心结构并未破坏,接着结构的进一步变化使活性逐步丧失,表明lra具有较强的抗变性能力。
Trichosanthin ( tcs ) is a single - chain ribosome inactivating protein . tcs belongs to a sort of metalloprotein , and ca2 + locates in its active center . it is isolated from trichosanthes kirilowii tubers of cucurbitaceae and is the active component of chinese drug tian hua fen 天花粉蛋白是从葫芦科植物栝楼块根中分离得到的一种单链核糖体失活蛋白,是中药天花粉的有效成分,具有重要的理论研究和实际应用价值。