Using transfac 4 . 0 and tssg tssh nsite of softbeny , we can see that a tata box lie in - 188bp - 198bp from transcriptional initiation site , there are several api , c / ebp binding motifs near it or in other 5 " flanking region , a c - fos response element is in - 1133bp - 1143bp from transcriptional initiation site 0软件和softbeny网站上tssg , tssh , nsi ’ fe软件共同分析,在a ? ibgp转录起始点上游j到一198区域存在tata盒,在其附近及其5 ’上游远端调节区存在多个api , c ebp结合位点,并且在转录起始点上游人到一处存在一个c fos结合基序。
In our study , we found that a - 1bgp expression is up - regulated in hepatoma cells treated with gh . it suggests that gh is capable of stimulating the expression of a - 1bgpin hepatoma cells . so a - 1 bgp may play a role in postnatal growth and intermediary metabolism which are major physiological actions of gh 为了了解gh是通过何种途径调节a ibgp表达,我们分析了a ibgp的5 ’端调控区,台果发现了普遍存在的api , c ebp结合基序,而且还存在着一个( , fos结合基序,所以推测gh可能通过诱导c fos , c一表达增高,结合于a ibgp调控区的特异性dna反应元件,促进它的表达。
The ir sequence of mxmybl is most homologous with that of atmyb ( 86 . 9 % ) and somewhat homologous with that of stmyb 1 ( 77 . 0 % ) ; there is very low homology among n - and c - terminal regions outside of the ir regions of all of the mybs ; the protein mxmybl contains a proline - rich region as well as a serine - rich region near the c - terminus , such structure motifs are implicated in transcriptional activation 9 ,与马铃薯stmyb的ir序列的同源性达77 0 ,所有这些nnrb蛋白除了瓜区具有较高的同源性外,其c端和n端几乎没有同源性。 mwyb蛋白的c一端还含有一个富含脯氨酸区,这样的结构基序可能具有激活转录的功能。
Thioredoxins , an ubiquitous small proteins with a redox active disulfide bridge in its conserved motif - cp ( g ) pc - , are universally distributed in eucaryote and procaryote and have a molecular mass of approximately 12kda . by its disulfide / dithiol interchange reaction , this protein can transmit the regulatory signals to seleted targets ( enzymes , transcription factors etc ) and plays an important role in many plant physiological processes that includes photosynthesis , dna synthesis , transcription , protein disulfide reduction , protein repair , filamentous phage assembly , cell apoptosis and seeds germinating and so on 该蛋白质中含有保守的- cp ( g ) pc -氨基酸活性基序,该基序中的两个半胱氨酸残基可通过巯基二硫键的转换实现其氧化还原状态的变化和电子氢的传递,对细胞中与氧化还原相关的多种生理过程的调节起重要作用。通过同许多酶类、蛋白类、细胞内活性因子相藕连, trx能对光合作用、 dna复制、基因转录、细胞凋亡和生长、噬菌体组装、蛋白质的还原和修复信号传导等生理过程产生影响和调节。